Electronic Submission Systems

The OHRPP new IRB submission system, named BruinIRB, will be live starting Monday April 5, 2021.

BruinIRB will be rolled out in phases and will eventually replace webIRB entirely. In this phase, phase 1, BruinIRB will be accepting the following submission types:

• Emergency Use
• Humanitarian Use Device (HUD)
• Right to Try
• Expanded Access (Drug and Biologics and Device)

If UCLA is relying on another IRB for a HUD or Expanded Access submission, submit these within webIRB until further notice. Contact irbreliance@research.ucla.edu for these submissions.

BruinIRB Protocol Templates

BruinIRB requires all submissions to upload a protocol document rather than completing questions within the application. To assist in the new protocol requirement, OHRPP has created protocol templates that can be used for each submission. The protocol templates contain all the required information required for IRB review.

Phase 1 protocol templates

• Emergency Use
• Humanitarian Use Device
• Right to Try
• Expanded Access – Please see OHRPP Guidance and Procedures: Use of Drugs and Biologics in Clinical Research and Treatment or OHRPP Guidance and Procedures: Use of Devices in Clinical Research and Treatment for required sponsor or FDA documents that will serve as a protocol.

Note: These protocol templates are also available within BruinIRB Library.

BruinIRB Training Guides

• Creating a New Study
• Create and Submit a Continuing Review or Modification
• Updating Your Contact Information and Profile
• How to Respond to IRB Requests
• Navigating BruinIRB for Researchers
• PI Assurances for a New Study