The Central Institutional Review Board (CIRB) Initiative is sponsored by the National Cancer Institute (NCI) in consultation with the Department of Health and Human Services (DHHS) Office for Human Research Protections (OHRP). The CIRB enables an investigator to enroll patients into adult and pediatric NCI-sponsored clinical trials significantly faster than when employing traditional method of IRB review. The NCI CIRB will serve as the IRB of record for these studies. A detailed description of this process is available on the CIRB website link indicated above.
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