The UC Memorandum of Understanding (MOU) establishes a reliance agreement between and among the Human Research Protection Programs at the ten campuses of the University of California and the Lawrence Berkeley National Laboratory. This MOU describes the procedures for the reliance by an IRB at a UC campus or at the Berkeley Lab on the review and approval of human subject research, by an IRB at another UC campus.

**For projects involving the five University of California biomedical campuses (UCLA, UCSD, UCI, UCD, UCSF), the SMARTIRB online reliance system or SMARTIRB letter of acknowledgement (LOA) will be used to formalize the reliance agreement.**

See the Procedures for the UC IRB Reliance MOU.


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Page Last Updated: October 3, 2023